Summary & Overview
CPT 99391: Preventive Medicine Visit for Established Infant Patients
CPT code 99391 represents a periodic comprehensive preventive medicine reevaluation and management visit for established infant patients under one year of age. This code is a cornerstone of pediatric preventive care, ensuring infants receive thorough health assessments, counseling, and appropriate immunizations during their first year. Nationally, this service is recognized as essential for early detection of health issues and for promoting healthy development in children.
Major commercial payers, including Aetna, Blue Cross Blue Shield, Cigna Health, and UnitedHealthcare, provide coverage for services billed under CPT code 99391. The publication offers insights into payer coverage, clinical benchmarks, and policy updates relevant to preventive medicine visits for infants. Readers will gain an understanding of the clinical context for this code, including its role in routine child health examinations, and learn about associated billing practices, common modifiers, and related codes for other age groups. The summary also highlights the importance of preventive medicine services in the broader healthcare landscape, emphasizing their value in supporting child health and wellness.
This article is designed for healthcare professionals, billing specialists, and policy analysts seeking a comprehensive overview of CPT code 99391, including payer coverage, clinical guidelines, and billing considerations for preventive medicine services in pediatric care.
CPT Code Overview
CPT code 99391 is used for periodic comprehensive preventive medicine reevaluation and management of an established patient who is an infant (age younger than 1 year). This service includes an age and gender appropriate history, examination, counseling, anticipatory guidance, risk factor reduction interventions, and the ordering of appropriate immunizations, laboratory, or diagnostic procedures. The typical site of service for this code is the office setting (Place of Service 11). This code is part of preventive medicine services for established patients, focusing on early childhood health maintenance and disease prevention.
Clinical & Coding Specifications
Clinical Context
A typical scenario for CPT code 99391 involves an established infant patient, younger than 1 year, presenting to a primary care office for a periodic preventive medicine visit. The clinical workflow includes obtaining an age-appropriate medical history, performing a comprehensive physical examination, providing counseling and anticipatory guidance to the parent or guardian, addressing risk factor reduction, and ordering appropriate immunizations and laboratory or diagnostic procedures as indicated. The visit is focused on health maintenance and early detection of potential issues, rather than management of acute or chronic illness.
Coding Specifications
-
Modifier
25: Used when a significant, separately identifiable evaluation and management service is performed by the same physician on the same day as another procedure or service. This may apply if, during the preventive visit, an additional E/M service is provided. -
Modifier
33: Indicates that the service provided is preventive in nature. This modifier is used to identify preventive services for payors, including Blue Cross Blue Shield, Cigna Health, Aetna, UnitedHealthcare, BUCA, and Medicare.
| Taxonomy Code | Specialty |
|---|---|
207Q00000X | Family Medicine |
- Provider taxonomy
207Q00000Xrepresents Family Medicine, which includes physicians providing comprehensive primary care across all ages, including infants.
Related Diagnoses
-
Z00.129: Encounter for routine child health examination without abnormal findings- Used when the preventive visit reveals no abnormal findings in the infant.
-
Z00.121: Encounter for routine child health examination with abnormal findings- Used when the preventive visit identifies abnormal findings requiring further evaluation.
-
Z76.2: Encounter for health supervision and care of other healthy infant and child- Used for general health supervision visits for healthy infants and children.
-
Z00.110: Health examination for newborn under 8 days old- Used for preventive visits for newborns less than 8 days old.
-
Z00.111: Health examination for newborn 8 to 28 days old- Used for preventive visits for newborns aged 8 to 28 days.
Each diagnosis code is relevant for documenting the clinical reason for the preventive medicine service provided under CPT code 99391, based on the infant's age and findings during the visit.
Related CPT Codes
-
99392: Periodic comprehensive preventive medicine reevaluation and management of an established patient; early childhood (age 1 through 4 years). Used for preventive visits in children older than 1 year. -
99393: Periodic comprehensive preventive medicine reevaluation and management of an established patient; late childhood (age 5 through 11 years). Used for preventive visits in school-aged children. -
99394: Preventive medicine reevaluation and management of an established patient; adolescent (age 12 through 17 years). Used for adolescent preventive visits. -
99395: Preventive medicine reevaluation and management of an established patient; 18 through 39 years. Used for adult preventive visits. -
99396: Preventive medicine reevaluation and management of an established patient; 40 through 64 years. Used for middle-aged adult preventive visits. -
99397: Preventive medicine reevaluation and management of an established patient; 65 years and older. Used for senior preventive visits.
These codes are age-specific alternatives to 99391 and are selected based on the patient's age at the time of the preventive visit. Only one code is used per visit, corresponding to the patient's age group.
National Reimbursement Benchmarks
National mean rates for CPT code 99391 show that UnitedHealth Group has the highest average reimbursement at $133.31, while Aetna is the lowest among the major commercial payers at $98.41. The BUCA average (Blue Cross Blue Shield, UnitedHealth Group, Cigna, Aetna) stands at $105.35. Medicare rates are not available in the input for comparison.
Rate dispersion, measured by the difference between the 75th and 25th percentiles, varies across payers. Aetna has a range of $45.50, Blue Cross Blue Shield $51.50, Cigna $72.00, UnitedHealth Group $73.83, and BUCA $52.51. Aetna exhibits the tightest spread, while UnitedHealth Group and Cigna show the widest, indicating greater variability in commercial reimbursement rates for this code.
The table and chart below present a detailed breakdown of national benchmarks for each payer.
Trek Health ingests and normalizes Transparency in Coverage data and payer policy updates to give provider organizations a clear view of how commercial reimbursement behaves across markets, payers, and services. Our platform transforms raw payer disclosures into structured intelligence that supports contract evaluation, payer negotiations, and service line strategy. By combining market benchmarks with ongoing policy visibility, Trek helps teams identify variability, risk, and opportunity in commercial reimbursement. The result is faster insight, stronger negotiating positions, and more informed financial decisions.